Aspirin intake can reduce death or severe illness in hospitalized coronavirus patients, a new study suggests.
The researchers discovered that a day-to-day low-dose pill could reduce the probability of being admitted to the ICU or being placed on a ventilator by over 40 percent.
The researchers, from the University of Maryland School of Medicine (UMSOM), explains that the outcomes gives ‘cautious optimism’ of the potency of this manageable and available drug to help deter drastic complications.
‘This is a critical finding that needs to be confirmed through a randomized clinical trial,’ said study leader Dr Jonathan Chow, assistant professor of anesthesiology at UMSOM.
‘If our finding is confirmed, it would make aspirin the first widely available, over-the-counter medication to reduce mortality in COVID-19 patients.’
For the research, the journal Anesthesia and Analgesia, the team observed the medical records of 412 COVID-19 patients doctored at University of Maryland Medical Center in Baltimore and three other hospitals along the East Coast.
Approximately one-quarter took a daily low-dose aspirin before or straight after they were admitted to manage cardiovascular disease.
Researchers monitored various characteristics like age, sex, race, body mass index and crucial conditions such as hypertension and diabetes.
Results also indicated that most importantly, the aspirin lessened the danger of death from covid-19 in the hospital by 47 percent compared to the people who were not taking aspirin.
No difference between patients in the aspirin group and the non-aspiring group in respects to so-called unfavorable events such as major bleeding.
Nevertheless, aspirin intake alters how the blood clots, and this might be the reason why aspirin is important.
‘We believe that the blood thinning effects of aspirin provides benefits for COVID-19 patients by preventing microclot formation,’ said co-author Dr Michael Mazzeffi, an associate professor of anesthesiology at UMSOM.
‘Patients diagnosed with COVID-19 may want to consider taking a daily aspirin as long as they check with their doctor first.’
Aspirin is however not meant to be used for prevention.
‘This study adds to the tremendous work our researchers are doing in the School of Medicine to help find new treatments against COVID-19 and save patients’ lives,’ said DR E. Albert Reece, Dean of USOM.
‘While confirmatory studies are needed to prove that aspirin use leads to better outcomes in COVID-19, the evidence thus far suggests that patients may want to discuss with their doctor whether it is safe for them to take aspirin to manage potentially prevent serious complications.’